The opportunistic pathogen Serratia marcescens utilises Type VI Secretion to target bacterial 1 competitors 2 3
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چکیده
The opportunistic pathogen Serratia marcescens utilises Type VI Secretion to target bacterial 1 competitors 2 3 Sarah L. Murdoch, Katharina Trunk, Grant English, Maximilian J. Fritsch, Ehsan Pourkarimi 4 & Sarah J. Coulthurst* 5 6 Division of Molecular Microbiology and Wellcome Trust Centre for Gene Regulation and 7 Expression, College of Life Sciences, University of Dundee, UK 8 9 10 Running title: Type VI Secretion in Serratia marcescens 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 These authors contributed equally. 33 34 35 *For correspondence: 36 37 Dr Sarah J. Coulthurst 38 39 Division of Molecular Microbiology 40 College of Life Sciences, University of Dundee 41 Dow Street 42 Dundee 43 DD1 5EH 44 UK 45 46 Tel: +44 1382 386208 47 Fax: +44 1382 388216 48 Email: [email protected] 49 50 Copyright © 2011, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Bacteriol. doi:10.1128/JB.05671-11 JB Accepts, published online ahead of print on 2 September 2011
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The opportunistic pathogen Serratia marcescens utilizes type VI secretion to target bacterial competitors.
The type VI secretion system (T6SS) is the most recently described and least understood of the protein secretion systems of Gram-negative bacteria. It is widely distributed and has been implicated in the virulence of various pathogens, but its mechanism and exact mode of action remain to be defined. Additionally there have been several very recent reports that some T6SSs can target bacteria rat...
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